Minoru Yoshida
RIKEN Center for Sustainable Resource Science, Japan
Biography
Minoru Yoshida received his PhD (1986) from the University of Tokyo, where he worked as Assistant and Associate Professors and accomplished mode-of-action studies on trichostatin A (TSA) and leptomycin B (LMB). He identified histone deacetylase and Crm1 as the specific targets of TSA and LMB, respectively. He moved to RIKEN as Chief Scientist in 2002, and has been playing a leading role in chemical biology.His work has unearthed new targets for drug discovery, and several inhibitors of these targets have come into practical use as anticancer drugs. He received many awards including Japan Academy Prize.
Abstract
Abstract : Chemical genomics for target identification of antifungal theonellamides
